

aml(boot)                                    R Documentation

_R_e_m_i_s_s_i_o_n _T_i_m_e_s _f_o_r _A_c_u_t_e _M_y_e_l_o_g_e_n_o_u_s _L_e_u_k_a_e_m_i_a

_A_r_g_u_m_e_n_t_s_:

    time: The length of the complete remission (in weeks).

    cens: An indicator of right censoring.  1 indicates that
          the patient had a relapse and so `time' is the
          length of the remission. 0 indicates that the
          patient had left the study or was still in remis-
          sion in October 1974, that is the length of remis-
          sion is right-censored.

   group: The group into which the patient was randomized.
          Group 1 received maintenance chemotherapy, group 2
          did not.

_S_U_M_M_A_R_Y_:

     The `aml' data frame has 23 rows and 3 columns.

     A clinical trial to evaluate the efficacy of mainte-
     nance chemotherapy for acute myelogenous leukaemia was
     conducted by Embury et al. (1977) at Stanford Univer-
     sity.  After reaching a stage of remission through
     treatment by chemotherapy, patients were randomized
     into two groups. The first group received maintenance
     chemotherapy and the second group did not.  The aim of
     the study was to see if maintenance chemotherapy
     increased the length of the remission.  The data here
     formed a preliminary analysis which was conducted in
     October 1974.

_D_A_T_A _D_E_S_C_R_I_P_T_I_O_N_:

     This data frame contains the following columns:

_S_O_U_R_C_E_:

     The data were obtained from

     Miller, R.G. (1981) Survival Analysis. John Wiley.

_O_T_H_E_R _R_E_F_E_R_E_N_C_E_S_:

     Davison, A.C. and Hinkley, D.V. (1997) Bootstrap Meth-
     ods and Their Application. Cambridge University Press.

     Embury, S.H, Elias, L., Heller, P.H., Hood, C.E.,
     Greenberg, P.L. and Schrier, S.L. (1977) Remission
     maintenance therapy in  acute myelogenous leukaemia.
     Western Journal of Medicine, 126, 267-272.

